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Blebbishield emergency program
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Blebbishield emergency program : ウィキペディア英語版
Blebbishield emergency program

Blebbishield emergency program is a process which acts as a last line of defense for cancer stem cells after induction of apoptosis where the apoptotic blebs fuse to shield the cells from the destructive force of apoptosis by forming blebbishields. Blebbishields in turn fuse to each other and generate cancer stem cell spheres, essentially shifting the balance of dying cells back towards survival.
==Discovery==
Blebbishields were first identified in human bladder cancer cell line RT4 (HTB-2: ATCC), referred to as RT4P (RT4 parent) in the initial report.〔Jinesh GG, Choi W, Shah JB, Lee EK, Willis DL, Kamat AM. (Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis ). Cell Death Differ. 2013 Mar;20(3):382-95.〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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